Florence, capital of Italy’s Tuscany region and birthplace of the Renaissance, is home to masterpieces of art and architecture. One of its most iconic sites is the Florence Cathedral, with its terra-cotta-tiled dome engineered by Brunelleschi and bell tower designed by Giotto. The Galleria dell'Accademia displays Michelangelo’s “David,” while the Uffizi Gallery exhibits preeminent works such as Botticelli’s “The Birth of Venus” and da Vinci’s “Annunciation.”